What Are The Side Effects Of Abacavir?

What is abacavir used for?

Abacavir is used along with other medications to treat human immunodeficiency virus (HIV) infection.

Abacavir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs).

It works by decreasing the amount of HIV in the blood..

What is HLA b5701 test?

The HLA-B*5701 test is used to determine potential risk for serious side-effects to a medication called abacavir. A positive test result means you have the HLA-B*5701 gene variant and have a higher risk of developing a potentially life-threatening reaction to abacavir.

What is abacavir sulfate?

abacavir sulfate A sulfate salt form of abacavir, a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS.

Why antiretroviral therapy is important?

Effective antiretroviral therapy is the most important intervention in terms of improving longevity and preventing opportunistic infections in patients with human immunodeficiency virus (HIV) infection.

What is abacavir hypersensitivity?

Abacavir hypersensitivity reaction affects 5 to 8% of patients and can be observed during the first 6 weeks of antiretroviral therapy. Symptoms of an abacavir hypersensitivity reaction include skin rash, fever, malaise, gastrointestinal symptoms, and respiratory symptoms.

What are the side effects of ritonavir?

Diarrhea, nausea, vomiting, heartburn, stomach pain, dizziness, tiredness, weakness, changes in taste, or tingling/numbness of mouth area may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Does Dolutegravir have side effects?

Many side effects from HIV medicines, such as nausea or occasional dizziness, are manageable. See the AIDSinfo fact sheet on HIV Medicines and Side Effects for more information. Some side effects of dolutegravir can be serious. Serious side effects of dolutegravir include allergic reactions and liver problems.

Does abacavir cause lipodystrophy?

Of the NRTIs, the thymidine analogues stavudine (d4T) and zidovudine (ZDV, previously known as AZT) are mostly directly implicated in lipodystrophy, particularly lipoatrophy; switching to a different NRTI such as tenofovir or abacavir can produce demonstrable increases in limb fat and can improve lipid profiles.

What are the side effect of lamivudine?

Side effects of lamivudine include fatigue, muscle aches, fever and chills, sore throat, nausea, stomach pain or cramps, and diarrhea. Serious side effects are rare, occurring in less than 1% of people taking lamivudine.

How does abacavir work?

Abacavir interferes with an enzyme called reverse transcriptase (RT), which is used by HIV-infected cells to make new viruses. Since abacavir inhibits, or reduce the activity of this enzyme, this drug causes HIV-infected cells to produce fewer viruses.

Is antiretroviral therapy expensive?

At present, an initial ART regimen for most PWH averages more than $36,000 per patient per year, and this annual cost is only going up: The average price increase has been 6% each year since 2012.

What does lamivudine cure?

Lamivudine (Epivir-HBV) is used to treat hepatitis B infection. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV and hepatitis B in the blood.

How long does it take for antiretrovirals to work?

The advantages of taking HIV treatment: (It might take up to six months on treatment to become undetectable.) You may have less illness, if HIV has been making you ill. The treatment will stop HIV from reproducing in your body. Your immune system will get stronger.

Is Lamivudine an antibiotic?

This combination antibiotic is used to treat various infections, including urinary tract infection and traveler’s diarrhea. Lamivudine may interact with these drugs. Talk to your doctor if you’re taking this antibiotic.

Why Lamivudine is called 3tc?

Lamivudine, sold under the brand name 3TC (Epivir in the US), is a type of antiretroviral (anti-HIV) drug called a nucleoside analogue or “nuke.” 3TC is used in combination with other antiretroviral drugs to treat (but not cure) HIV. 3TC is also found in these medicines: Kivexa – 3TC + abacavir.

Is Antiretroviral Therapy Effective?

Antiretroviral therapy is an effective treatment for HIV. It does not cure the condition, but it can reduce the viral load to undetectable levels. This means that the virus is not transmittable through sexual activity and a person’s immune system can recover.

Who makes abacavir?

ViiV HealthcareIt is made by ViiV Healthcare, the company that also produces zidovudine (AZT, Retrovir), lamivudine, (3TC, Epivir) and dolutegravir (Tivicay). Abacavir is also available as part of the following combinations: Kivexa (600mg abacavir combined with 300mg lamivudine).